Foreign News
Australian Breakthrough Blood Stem Cell Research to Possibly Change Future Medicine
New discoveries about embryonic blood stem cell creation by Australian researchers could one day eliminate the need for stem cell donors.
The discovery was made independently by both biomedical engineers and medical researchers of the University of New South Wales (UNSW) Sydney, as part of a move in regenerative medicine.
This was to move toward the use of “induced pluripotent stem cells’’ to treat disease.
“This means that instead of using live human or animal embryos, stem cells are reverse engineered from adult tissue cells.
’’Two studies emerged by two independent groups of researchers from UNSW, which takes the medical community one step closer to achieving this.
One of the studies led by Jingjing Li and published in Cell Reports and revealed on Wednesday, details how a simulation of an embryo’s beating heart.
The embryo’s beating heart using a microfluidic device in the lab led to the development of human blood stem cell precursors.
This, as the name suggests, is stem cells on the verge of becoming blood stem cells.
“We made a device mimicking the heart beating and the blood circulation and an orbital shaking system which causes shear stress.
“Or friction, of the blood cells as they move through the device or around in a dish,’’ Li explained.
The device successfully replicated the process in which precursor blood stem cells differentiate into various blood components.
The other study was revealed in an article published in Nature Cell Biology, which saw John Pimanda and Vashe Chandrakanthan of UNSW Medicine and Health detail their research on how blood stem cells are created in embryos.
This was done by looking at the mechanism used naturally in mice to make blood stem cells from the cells that line blood vessels, known as endothelial cells.
While it was already known that this process took place, Pimanda explained that up until now the identity of the cells that regulate this process has been a mystery.
According to Chandrakanthan, knowing the identity of these cells provides medical researchers with important clues as to how endothelial cells could be triggered to produce blood stem cells.
Both groups of researchers claimed that this is an important step toward solving many challenges limiting regenerative medical treatments today.
Such as donor shortages, rejection of donor tissue cells and ethical issues associated with using IVF embryos. (NAN)
Foreign News
President Yoon Banned from Leaving South Korea
The South Korean Government ordered an overseas travel ban on President Yoon Suk Yeol.The South Korean news agency Yonhap reported on Monday that the travel ban is due to the ongoing investigation into Yoon, which involves suspicion of high treason.Yoon unexpectedly imposed martial law on his country last Tuesday night, but hours later, after massive political resistance, he repealed the order.
On Saturday evening, a motion by the opposition to impeach the president in parliament failed. However, public pressure against the 63-year-old continues. (dpa/NAN)Foreign News
Israel Threatens to Expand War if Hezbollah Truce Collapses
Israel threatened on Tuesday to return to war in Lebanon if its truce with Hezbollah collapses and said this time its attacks would go deeper and target the Lebanese state itself, after the deadliest day since the ceasefire was agreed last week.
In its strongest threat since the truce was agreed to end 14 months of war with Hezbollah, Israel said it would hold Lebanon responsible for failing to disarm militants who violated the truce.
“If we return to war we will act strongly, we will go deeper, and the most important thing they need to know: that there will be no longer be an exemption for the state of Lebanon,” Defence Minister Israel Katz said.
“If until now we separated the state of Lebanon from Hezbollah… it will no longer be (like this),” he said during a visit to the northern border area.
Despite last week’s truce, Israeli forces have continued strikes in southern Lebanon against what they say are Hezbollah fighters ignoring the agreement to halt attacks and withdraw beyond the Litani River, about 30 km (18 miles) from the frontier.
On Monday, Hezbollah shelled an Israeli military post, while Lebanese authorities said at least 12 people were killed in Israeli airstrikes on Lebanon.
Katz called the Hezbollah attack “the first test” and described Israel’s strikes as a strong response.
The Beirut government must “authorise the Lebanese army to enforce their part, to keep Hezbollah away beyond the Litani, and to dismantle all the infrastructure,” Katz said.
“If they don’t do it and this whole agreement collapses then the reality will be very clear.”
Top Lebanese officials urged Washington and Paris to press Israel to uphold the ceasefire, after dozens of military operations on Lebanese soil that Beirut has deemed violations, two senior Lebanese political sources told Reuters on Tuesday.
The sources said caretaker Prime Minister Najib Mikati and Speaker of Parliament Nabih Berri, a close Hezbollah ally who negotiated the deal on behalf of Lebanon, spoke to officials at the White House and French presidency late on Monday.
Mikati, quoted by the Lebanese news agency, said that diplomatic communications had intensified since Monday to stop Israeli violations of the ceasefire.
He also said a recruitment drive was under way by the Lebanese army to strengthen its presence in the south.
U.S. State Department spokesperson Matt Miller told reporters on Monday that the ceasefire “is holding” and that the U.S. had “anticipated that there might be violations”.
Neither the French presidency nor the foreign ministry were immediately available to comment.
French Foreign Minister Jean-Noel Barrot spoke to his Israeli counterpart Gideon Saar on Monday, saying both sides should adhere to the ceasefire.
The truce came into effect on Nov. 27 and prohibits Israel from conducting offensive military operations in Lebanon, while requiring Lebanon to prevent armed groups including Hezbollah from launching attacks on Israel.
It gives Israeli troops 60 days to withdraw from south Lebanon.
A mission chaired by the United States is tasked with monitoring, verifying, and helping enforce the truce, but it has yet to begin work.
Berri on Monday called on the mission to “urgently” ensure Israel halts its breaches, saying Beirut had logged at least 54 Israeli violations of the ceasefire so far.
Israel has said its continued activity in Lebanon is aimed at enforcing the ceasefire.
Lebanon’s Mikati met in Beirut on Monday with U.S. General Jasper Jeffers, who will chair the monitoring committee.
Two sources familiar with the matter told Reuters that France’s representative to the committee, General Guillaume Ponchin, would arrive in Beirut on Wednesday and that the committee would hold its first meeting on Thursday.
“There is an urgency to finalise the mechanism, otherwise it will be too late,” the source said, referring to Israel’s gradual intensification of strikes even with the truce in place. (Reuters/NAN)
Foreign News
Starmer Rules out Re-running UK Election as Petition Gets Signatures
British Prime Minister Keir Starmer has ruled out calling another general election, but said he is “not surprised” some people who did not support his party, Labour, might want a second poll.
A petition on Parliament’s website calling for another election has now been signed by more than two million people.
“I would like there to be another general election,” it reads.
“I believe the current Labour Government have gone back on the promises they laid out in the lead-up to the last election.
”Asked about the petition on ITV’s “This Morning” programme on Monday, Starmer said: “Look, I remind myself that very many people didn’t vote Labour at the last election.
“I’m not surprised that many of them want a re-run. That isn’t how our system works.
“There will be plenty of people who didn’t want us in the first place.
“So, what my focus is on is the decisions that I have to make every day.”
He characterized decisions taken so far by his government as “tough but fair.”
Starmer and his ministers have faced a particularly strong backlash for limiting winter fuel payments to only the poorest pensioners.
Farmers have also protested over changes to inheritance tax which they claim could affect the future of their businesses.
As he marks five months as prime minister, Starmer acknowledged the job has been difficult, but added: “I wouldn’t swap a single day in opposition for a day in power.
“It’s much better to be in power to do things, rather than the frustration, as I found it, in opposition for all of those long years where we were just able to say what we would do.”
The petition calling for another general election is open for signatures until May 2025.
While the vast majority of those signing it are from the UK, it has also gained support from other countries.
More than 1,200 people from the U.S. have added their names to it, with similar a number from France doing the same.
American signatories may have been made aware of the petition by Elon Musk, the businessman and ally of President-elect Donald Trump.
He shared the petition on X, the social media site he owns formerly known as Twitter, claiming “the people of Britain have had enough of a tyrannical police state”.
Starmer’s office sought to avoid being drawn into a war of words with Mr Musk.
The prime minister’s official spokesman added Starmer was “focused on the issues that matter most to the British people.”
Although it has garnered media attention and millions of signatures, it is far from the largest petition received through the Parliament website, or the one which has seen the most rapid take-up.
In 2019, some 6.1 million people signed a petition calling for the revocation of Article 50 and for the United Kingdom to remain in the European Union, four million of whom did so in 48 hours.
The second most-signed petition gained 4.1 million signatures.
The 2016 petition called for a second referendum on the UK’s membership of the European Union following the Brexit vote.
Because the election petition has received 10,000 signatures, ministers will issue a response to it.
MPs may consider it further in a Westminster Hall debate because it has been signed by more than 100,000 people, although this is not guaranteed.
A petition which has successfully made it to debate is one calling for social media companies to ban under 16-year-olds from their platforms after it received more than 110,00 signatures.
Another calling for the law around school term-time holidays to be relaxed, which received 250,000 signatures, was due for debate on Monday afternoon.
Michael Westwood, the man who started the petition, has confirmed he voted Conservative at the summer election.
But he told Talk TV he did not know if this would be the case again, adding: “One thing’s for certain, I wouldn’t be voting Labour.”
Among those sharing the petition online was retired actor Sir Michael Caine, who has been critical of Labour governments in the past. (PA Media/dpa/NAN)