Health
COVID-19: NPHCDA Explains Breakthrough Infection in Vaccinated People in Nigeria

The National Primary Health Care Development Agency (NPHCDA), has said that people with breakthrough infection after incomplete and complete vaccination have less symptoms and less severe disease, and – importantly after full vaccination less prolonged COVID-19 symptoms.
The Executive Director of National Primary Health Care Development Agency, (NPHCDA), Dr Faisal Shuaib, gave the explanation to newsmen on Tuesday, during the National Vaccination update on Friday.
The Breakthrough infection is a case of illness in which a vaccinated individual becomes sick from the same illness that the vaccine is meant to prevent.
Shuaib disclosed that there have been report of cases where individuals contracted the virus 14 days after being fully vaccinated in Nigeria.
“If a person gets infected with the SARS-CoV-2 virus 14 days after the second shot of the vaccine, it is called a ‘breakthrough infection’. The two-week window is the time it takes for the body to produce necessary antibodies following a shot of the vaccine.
“A ‘breakthrough infection’ refers to the virus being able to penetrate the protective barrier of antibodies.
“The observation is that in these individuals, the disease is usually milder than those who were unvaccinated. Vaccination prevents one from severe disease, hospitalization and death.
“If our communities continue to remain unvaccinated, we will keep endangering our communities, especially those who are vulnerable,” he said.
Shuaib explained that COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after vaccination.
The NPHCDA added that this group of vaccinated individuals with COVID-19, are more likely to be completely asymptomatic than unvaccinated people.
“The chance of a breakthrough infection is low. It would be significantly lower if more people are vaccinated.
“Your individual risk for COVID-19 after vaccination also depends on the individual, your overall health, the precautions you take and how often you are exposed to unvaccinated people who could be infected,” he noted.
He disclosed that the agency had introduced a special vaccination exercise that would enable members of staff and retirees of public and private sector firms to be vaccinated in their office premises.
According to him, the platform was created in pursuant of the government’s mandate of making vaccination compulsory for all civil servants, as well as in recognition of the fact that some workers may find it difficult to leave their duty posts to vaccination sites.
“We have introduced and expanded in-situ corporate vaccination. This entails making special arrangement for eligible staff, dependents and retirees of Ministries, Departments and Agencies of Government (MDAs) and the private sector to get vaccinated in their office premises.
“MDAs, public and private corporate organization that require staff to be vaccinated should visit www.nphcda.gov.ng to fill the request form. These services would be provided at no cost to the Ministries, agency/cooperate bodies,” he said.
Shuaib, speaking further, disclosed that Nigeria had been categorized as an ‘amber’ country by the government of United kingdom based on the number of populations immunized and incidence rates of COVID-19 infection.
“Travellers from Amber’s countries, according to him, are placed under compulsory isolation by the United Kingdom’s government, whether or not such a person has been vaccinated,” he noted.
He said, “We have been inundated with questions about why the UK insists Nigerians who have been fully vaccinated are still required to isolate upon arrival in the UK.
“Nigeria alongside countries like France and the Netherlands are listed as amber countries by the UK Government based on criteria such as the number of populations immunized and incidence rates of COVID-19 infection.
“Individuals from Countries listed as amber countries are required by the UK Government to take a COVID-19 test upon arrival and be quarantined for a few days,” he said.
According to the Agency, as of 6th September, 2021, a total of 3,600,858 Nigerians have received their first dose of COVID-19 vaccine.
“This is made up of 2,551,738 persons vaccinated with AstraZeneca vaccine and 1,049,120 persons vaccinated with Moderna vaccine, bringing the total number of persons vaccinated with AstraZeneca vaccine to 1,576,011,” he stated.
Meanwhile, the World Health Organization (WHO) Country Representative, Dr Walter Kazadi Mulombo, said globally, WHO is calling for a moratorium on boosters until at least the end of September, to enable at least 10 percent of the population of every country to be vaccinated.
Mulombo, who was represented by Dr. Kofi Boateng, EPI Focal Point, Universal Health Coverage (UHC), added that vaccine injustice is a shame on all humanity and if the world do not tackle it together, it would prolong the acute stage of this pandemic for years when it could be over in a matter of months.
According to him; “In Africa, the third wave appears to have stabilized but the number of new cases is still very high with almost 248 000 reported in the past week.
“The trend we see is that each new wave strikes Africa faster and harder, reaching a higher number of new cases more rapidly than the previous wave. This puts an increasing strain on already stretched health facilities and health workers.
“It is useful to point out that vaccine supplies to Africa continue to rise, spurring vaccine uptake.
“The increasing vaccine supplies raise hopes that the continent will meet the target of vaccinating 10% of the population by the end of September,” he stressed.
Also speaking, the representative of the United Nation’s Children Fund (UNICEF) in Nigeria, Dr. Gupta Gagan, commended the NPHCDA and its leadership for the ongoing COVID-19 vaccination drive.
Gupta said the challenge faced in the administration of the vaccine would be reaching out to citizens to go and receive their second doses.
“All those who have received the first dose should please go back for their second dose because if you don’t you should know that you are not fully protected,” he noted.
He, however, assured that Nigeria would meet the WHO target of vaccinating 10% of its population by the end of September. (NAN)
Health
Experts Seek Unified Action against Cervical Cancer

Torough David, Abuja
Stakeholders across health sectors have called for urgent, coordinated investment in prevention, equitable HPV vaccine access and harmonized health data to accelerate progress towards elimination of cervical cancer across Africa.
They made the call on Wednesday, during a panel session with the Theme ”Accelerating Cervical Cancer Elimination in Nigeria, From Policy to Practice”.
Head of Division, Maternal, Newborn, Child and Adolescent Health, Africa CDC, Dr Fidele Ngabo Gaga, highlighted its efforts to harmonise and aggregate health data across all 55 African Union (AU) Member States.
“We are developing a continent-wide data-sharing agreement and centralised repository to support data upstreaming and policy development.
“The goal is to present unified data at AU Summits, helping countries make evidence-based decisions,” Gaga said:
Prof. Imran Morhason-Bello, a leading gynaecologic oncologist from the University College Hospital, Ibadan, made a compelling financial case for prioritising prevention over treatment.
“Screening just between 2023 and 2027 will cost Nigeria N351 billion.
“But treating 10,000 women with invasive cervical cancer from 2027 to 2030 could cost us N1.4 trillion. Prevention is not only more humane, it is far more cost-effective,” he said.
Morhason-Bello also addressed innovations such as self-sampling for HPV testing, already being implemented in Nigeria through implementation science.
“Women receive a self-sampling kit, return it the same day, and positive results are treated before noon.
“It is happening in markets and schools. It is not a pilot, it is real.
“We have even developed a mobile app (available in multiple languages and offline) to guide women through the self-sampling process, increasing accessibility in low-resource settings,” he said.
External Affairs Director for MSD, Sub-Saharan Africa, Vuyo Mjekula, addressed one of the most common myths around the HPV vaccine rollout.
“Let me be clear, there is no shortage of HPV vaccines. If anyone tells you otherwise, call me directly. The real issue is equity and strategic allocation,” she said.
Mjekula recalled early proposals that included boys in HPV vaccination efforts, but warned that without careful planning, some countries would be left out entirely.
She called for one national policy that ensures equitable access to vaccines and services, especially for the most vulnerable girls.
“This is not about science alone. A dose costing N125,000 may be affordable to some, but to a woman in a rural village, it is like N10 million.
“If she must choose between survival and feeding her children, the answer is obvious,” she said.
She applauded Nigeria’s progress, noting that since the national rollout, the number of vaccinated girls across the continent has more than doubled, driven primarily by Nigeria’s leadership.
Mjekula also made an appeal for multi-sectoral collaboration, urging the involvement of private sector giants, from banks to telecoms and philanthropic foundations.
“Health is not just the government’s responsibility. We need to imagine beyond the healthcare we can afford with public funds and work toward the healthcare we want as a society,” she said.
She also called for a business case for investment in HPV prevention and cancer control, saying the task force must work hand-in-hand with all stakeholders.
“Let us go far together. If you want to go quickly, go alone. But if you want to go far, go together,” she said.
The symposium concluded with a call to integrate cancer screening into primary health care services.
It also called for the deployment of cost-effective technologies like self-sampling, addressing myths around vaccine shortages, and ensuring gender-sensitive, data-informed policies.
As Nigeria and the continent advance towards achieving the WHO 90-70-90 cervical cancer elimination targets, the message from experts was clear: “Let us do big and let us do it together”.
Health
89% of Infants Vaccinated Globally in 2024, WHO, UNICEF Warn of Risks

The United Nations agencies have reported that in 2024, approximately 89 per cent of infants worldwide, about 115 million children, received at least one dose of the diphtheria, tetanus, and pertussis (DTP) vaccine.This update comes from new national immunisation coverage data released on July 14 by the World Health Organisation (WHO) and the United Nations Children’s Fund (UNICEF).
Compared to 2023, an additional 171,000 children received at least one vaccine dose, and one million more completed the full three-dose DTP series. While these gains are modest, they reflect ongoing global efforts to protect children in spite of rising challenges.However, nearly 20 million infants still missed at least one DTP vaccine dose in 2024, including 14.3 million “zero-dose” children who never received any vaccine.This figure exceeds the 2024 target by four million, putting global immunisation goals outlined in the Immunisation Agenda 2030 at risk.WHO Director-General Dr Tedros Ghebreyesus emphasised the life-saving power of vaccines, stating, “It’s encouraging to see an increase in children vaccinated, but we still have much work to do. “Cuts in aid and vaccine misinformation threaten to reverse decades of progress.”He highlighted factors contributing to under-vaccination, including limited healthcare access, supply disruptions, conflict, and misinformation.“Data from 195 countries show 131 have consistently reached at least 90 per cent coverage with the first DTP dose since 2019. Yet, progress is stalling in 47 countries, with 22 nations seeing declines after previously meeting this target.”Tedros warned that conflict and humanitarian crises significantly undermined vaccination efforts.“A quarter of the world’s infants live in 26 fragile or conflict-affected countries, which account for half of all unvaccinated children globally.“In these areas, unvaccinated children rose from 3.6 million in 2019 to 5.4 million in 2024, highlighting an urgent need for integrated immunisation in humanitarian responses.“Immunisation coverage in 57 low-income countries supported by Gavi, the Vaccine Alliance, improved in 2024, reducing the number of under-vaccinated children by about 650,000.“Yet, some upper-middle- and high-income countries face early signs of declining coverage, which increases the risk of disease outbreaks.”UNICEF Executive Director Catherine Russell welcomed the progress but warned millions of children remained vulnerable to preventable diseases.She called for urgent action to overcome barriers such as shrinking health budgets, fragile systems, misinformation, and conflict-related access issues.Russell noted encouraging expansions in vaccines against HPV, meningitis, pneumococcal disease, polio, and rotavirus.“Global HPV vaccine coverage among eligible adolescent girls rose from 17 per cent in 2019 to 31 per cent in 2024, although it remains far below the 90 per cent target set for 2030.”Gavi CEO Dr Sania Nishtar added that while lower-income countries protected more children than ever, population growth, fragility, and conflict continued to hamper equity in vaccination efforts.She highlighted improvements in measles coverage but cautioned that it still fell short of the 95 per cent threshold required to prevent outbreaks.“Measles outbreaks nearly doubled from 33 countries in 2022 to 60 in 2024.”Nishtar stressed that funding shortfalls, instability, and rising misinformation threaten to stall or reverse progress, risking increased deaths from vaccine-preventable diseases.WHO and UNICEF called on governments and partners to close funding gaps for Gavi’s 2026–2030 strategic cycle to protect millions of children.They also urged strengthening immunisation efforts in conflict-affected and fragile settings, and prioritising locally led strategies and increased domestic investment in primary healthcare systems.Additionally, the agencies emphasised the need to counter vaccine misinformation through evidence-based campaigns.They also called for greater investment in robust data collection and disease surveillance systems to guide effective immunisation programmes. (NAN)Health
Nigeria Records 145 Lassa Fever Deaths, as Fatality Rate Increases

Nigeria has recorded 145 deaths from Lassa fever as of 2025 Epidemiological Week 25, with a case fatality rate (CFR) of 18.6 percent.
The Nigeria Centre for Disease Control and Prevention (NCDC), disclosed this in its latest report via its official website during the weekend in Abuja.
The NCDC said the week 25 figure marks an increase from 17.
6 percent reported for the same period in 2024.The report, which covered the week of June 16–22, revealed that 781 confirmed cases were reported out of 5,943 suspected cases across 20 states and 101 Local Government Areas (LGAs).
In the current reporting week, 10 new confirmed cases were reported in Ondo and Edo states with a slight increase from the eight cases recorded the previous week.
According to NCDC, 91 per cent of all confirmed cases in 2025 were reported from five states of Ondo (31%), Bauchi (24%), Edo (17%), Taraba (16%) and Ebonyi (3%).
It said that the disease continues to affect young adults predominantly, within the 21 to 30 age group most impacted. Males were slightly more affected, with a male-to-female ratio of 1:0.8.
The Nigerian public health agency, said that despite a decline in the overall number of suspected and confirmed cases compared to 2024, the rise in CFR is raising concerns among health experts.
The agency highlighted late presentation of cases, high treatment costs, and poor health-seeking behaviour as contributing factors to the increased fatality.
It said that no new infections among health workers were recorded in the reporting week, though 23 healthcare workers have been affected cumulatively this year.
The NCDC said it is currently in collaboration with partners, such as the World Health Organisation (WHO), the United States Centers for Disease Control and Prevention (US CDC), ALIMA, the Institute of Human Virology Nigeria (IHVN) and others.
The collaborations, it stated further, have intensified multi-sectoral response efforts to combat the spread of Lassa fever.
It said that, as part of these efforts, Integrate clinical trials are currently ongoing in Ondo State, with After Action Reviews (AARs) conducted in both Ondo and Ebonyi to evaluate the response to the outbreak.
The agency said that clinician sensitisation, community engagement activities and environmental response campaigns have been carried out in identified hotspot areas.
In addition, the NCDC said that it has deployed 10 national rapid response teams to various states, adopting a one health approach to disease control.
To further strengthen infection prevention and control (IPC), the agency launched an IPC e-learning platform and distributed updated Viral Hemorrhagic Fever (VHF) guidelines to health facilities across the country.
The agency said that other efforts also included active contact tracing, surveillance, media engagement and geospatial risk mapping, alongside regular webinars for clinicians and capacity-building sessions nationwide.
The NCDC identified key challenges including poor environmental sanitation and low community awareness, particularly in high-burden LGAs.
It also said that sustained efforts were needed to curb the fatality rate, ensure early detection, and improve public health outcomes.
The NCDC advised Nigerians to maintain proper hygiene, avoid contact with rodents, and seek medical help promptly when experiencing symptoms such as fever, sore throat, vomiting, or unexplained bleeding.
Lassa fever, which was first identified in 1969 in Lassa, Borno, is endemic in Nigeria, with outbreaks occurring annually.
Symptoms range from mild fever and joint pain to severe bleeding from the nose, mouth, and gastrointestinal tract.
The disease is fatal in about 20 percent of cases, particularly when treatment is delayed.
Across West Africa, hundreds of thousands are infected annually, experiencing symptoms such as fever, vomiting and, in severe cases, bleeding.
One of the most troubling complications is hearing loss, which affects about 25 percent of survivors.
The estimated fatality rate is one per cent, but during outbreaks, mortality can rise significantly, particularly among pregnant women and healthcare workers.
In spite of its significant health impact, Lassa fever remains one of the most neglected diseases, with limited resources allocated to its preventions and treatments.
Currently, no licensed vaccines exist, although around 20 candidates are in development, with the most advanced in Phase IIa clinical trials.