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COVID-19: NPHCDA Explains Breakthrough Infection in Vaccinated People in Nigeria

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The National Primary Health Care Development Agency (NPHCDA), has said that people with breakthrough infection after incomplete and complete vaccination have less symptoms and less severe disease, and – importantly after full vaccination less prolonged COVID-19 symptoms.

The Executive Director of National Primary Health Care Development Agency, (NPHCDA), Dr Faisal Shuaib, gave the explanation to newsmen on Tuesday, during the National Vaccination update on Friday.

The Breakthrough infection is a case of illness in which a vaccinated individual becomes sick from the same illness that the vaccine is meant to prevent.

Shuaib disclosed that there have been report of cases where individuals contracted the virus 14 days after being fully vaccinated in Nigeria.

“If a person gets infected with the SARS-CoV-2 virus 14 days after the second shot of the vaccine, it is called a ‘breakthrough infection’. The two-week window is the time it takes for the body to produce necessary antibodies following a shot of the vaccine.

“A ‘breakthrough infection’ refers to the virus being able to penetrate the protective barrier of antibodies.

“The observation is that in these individuals, the disease is usually milder than those who were unvaccinated. Vaccination prevents one from severe disease, hospitalization and death.

“If our communities continue to remain unvaccinated, we will keep endangering our communities, especially those who are vulnerable,” he said.

Shuaib explained that COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after vaccination.

The NPHCDA added that this group of vaccinated individuals with COVID-19, are more likely to be completely asymptomatic than unvaccinated people.

“The chance of a breakthrough infection is low. It would be significantly lower if more people are vaccinated.

“Your individual risk for COVID-19 after vaccination also depends on the individual, your overall health, the precautions you take and how often you are exposed to unvaccinated people who could be infected,” he noted.

He disclosed that the agency had introduced a special vaccination exercise that would enable members of staff and retirees of public and private sector firms to be vaccinated in their office premises.

According to him, the platform was created in pursuant of the government’s mandate of making vaccination compulsory for all civil servants, as well as in recognition of the fact that some workers may find it difficult to leave their duty posts to vaccination sites.

“We have introduced and expanded in-situ corporate vaccination. This entails making special arrangement for eligible staff, dependents and retirees of Ministries, Departments and Agencies of Government (MDAs) and the private sector to get vaccinated in their office premises.

“MDAs, public and private corporate organization that require staff to be vaccinated should visit www.nphcda.gov.ng to fill the request form. These services would be provided at no cost to the Ministries, agency/cooperate bodies,” he said.

Shuaib, speaking further, disclosed that Nigeria had been categorized as an ‘amber’ country by the government of United kingdom based on the number of populations immunized and incidence rates of COVID-19 infection.

“Travellers from Amber’s countries, according to him, are placed under compulsory isolation by the United Kingdom’s government, whether or not such a person has been vaccinated,” he noted.

He said, “We have been inundated with questions about why the UK insists Nigerians who have been fully vaccinated are still required to isolate upon arrival in the UK.

“Nigeria alongside countries like France and the Netherlands are listed as amber countries by the UK Government based on criteria such as the number of populations immunized and incidence rates of COVID-19 infection.

“Individuals from Countries listed as amber countries are required by the UK Government to take a COVID-19 test upon arrival and be quarantined for a few days,” he said.

According to the Agency, as of 6th September, 2021, a total of 3,600,858 Nigerians have received their first dose of COVID-19 vaccine.

“This is made up of 2,551,738 persons vaccinated with AstraZeneca vaccine and 1,049,120 persons vaccinated with Moderna vaccine, bringing the total number of persons vaccinated with AstraZeneca vaccine to 1,576,011,” he stated.

Meanwhile, the World Health Organization (WHO) Country Representative, Dr Walter Kazadi Mulombo, said globally, WHO is calling for a moratorium on boosters until at least the end of September, to enable at least 10 percent of the population of every country to be vaccinated.

Mulombo, who was represented by Dr. Kofi Boateng, EPI Focal Point, Universal Health Coverage (UHC), added that vaccine injustice is a shame on all humanity and if the world do not tackle it together, it would prolong the acute stage of this pandemic for years when it could be over in a matter of months.

According to him; “In Africa, the third wave appears to have stabilized but the number of new cases is still very high with almost 248 000 reported in the past week.

“The trend we see is that each new wave strikes Africa faster and harder, reaching a higher number of new cases more rapidly than the previous wave. This puts an increasing strain on already stretched health facilities and health workers.

“It is useful to point out that vaccine supplies to Africa continue to rise, spurring vaccine uptake.

“The increasing vaccine supplies raise hopes that the continent will meet the target of vaccinating 10% of the population by the end of September,” he stressed.

Also speaking, the representative of the United Nation’s Children Fund (UNICEF) in Nigeria, Dr. Gupta Gagan, commended the NPHCDA and its leadership for the ongoing COVID-19 vaccination drive.

Gupta said the challenge faced in the administration of the vaccine would be reaching out to citizens to go and receive their second doses.

“All those who have received the first dose should please go back for their second dose because if you don’t you should know that you are not fully protected,” he noted.

He, however, assured that Nigeria would meet the WHO target of vaccinating 10% of its population by the end of September. (NAN)

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Nigeria Records 15,000 AIDS-related Deaths Annually-NACA

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The National Agency For the Control of Aids (NACA) says no fewer than 15,000 AIDS-related deaths occur each year in Nigeria.The Director-General, NACA, Mrs Temitope Ilori stated this on Thursday in Abeokuta during an advocacy visit focused on achieving an AIDS-Free Generation and building a sustainable HIV response in Ogun.

Ilori, represented by Dr James Anenih, the Director of Community Prevention and Care Service, noted that approximately 140,000 children between the ages of 0 to 14 were living with HIV.
She added that 22,000 new HIV infections were recorded so far this year.She expressed concern over thePrevention of Mother-to-Child Transmission (PMTCT), paediatric HIV coverage remains below 33 per cent of the 95 per cent target.
She said hat Nigeria continues to face a significant challenge in preventing mother-to-child transmission of disease.Ilori appreciated the Ogun government for equipping selected health facilities to provide anti-retroviral therapy.She however expressed concerns that the state has a higher prevalence of 1.6 per cent than the national average of 1.4 per cent and the South West average of 1.2 per cent.“We acknowledge the great work your excellency has done in upgrading and equipping selected health facilities to provide anti-retroviral therapy (ART) from 22 sites in 2019 to 28 sites in 2023.“Also, the commissioning of the One-Stop-Shop and Community ART (CART) in Ogun East and Ogun West.“It is imperative to note that Ogun state has an HIV prevalence greater than the national average of 1.4 per cent and the South West average of 1.2 per cent.“There is an urgent need to halt and reverse the prevalence of the state from its current level of 1.6 per cent,” she said.Ilori said that no child in Ogun should be born with HIV, just as she tasked all pertinent partners to compile a comprehensive line list of children affected to expedite the country’s pediatric ART program.“The expectation is to have an AIDS-free generation at this point we are trying to make sure that all hands are on deck.“We’re looking at all of the various resources available to us and holding ourselves accountable so we can do more with reducing mother to child transmission or reducing the number of children born HIV positive,” Ilori added.In her response, the Commissioner for Health, Dr Tomi Coker stressed that the state’s HIV prevalence rate was critical.She commended the agency for visiting and inaugurating an 18-man PMTCT and Paediatric ART committee.She said that the committee would supervise the care of HIV-positive pregnant women to ensure that they do not have sufficient virus to infect their unborn children.Coker added that the committee would also place children who are positive on treatment to avoid the spread.NAN recalls that NACA said in 2023 alone, Nigeria recorded 75,000 new HIV infections and 45,000 HIV-related deaths.This the agency had said was alarming surge highlights significant lapses in the national response to this epidemic.(NAN)

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Lassa Fever: Nigeria Records 174 Deaths, 1,035 Confirmed Cases from January to October – FG

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By Laide Akinboade, Abuja

The Federal Government, FG, on Tuesday said as of October 13th, Nigeria has recorded 8,569 suspected cases, 1,035 confirmed cases, and 174 deaths of Lassa Fever, have been reported across 28 states and 129 Local Government Areas, LGAs.

Director General, Nigeria Centre for Disease Control and Prevention, NCDC, Dr.

Jide Idris, stated this while briefing the media, in Abuja, on prevention and creating awareness on Lassa Fever and Cerebrospinal Meningitis (CSM), in the country.

He said considering a steady increase in the number of states reporting Lassa fever cases, it is imperative to prevent, detect, and respond to cases of Lassa fever across the country.

According to the DG, “We have continued to see a steady increase in the number of states reporting Lassa fever cases. This rise is due, in part, to improved surveillance, better community awareness, environmental degradation from climate change, and other harmful human activities. In 2022, Nigeria reported 1,067 confirmed cases across 27 states and 112 LGAs. In 2023, 28 states and 114 LGAs reported confirmed cases, with 9,155 suspected cases, 1,270 confirmed cases, and 227 deaths.

“As of October 13, 2024, 8,569 suspected cases, 1,035 confirmed cases, and 174 deaths have been reported across 28 states and 129 LGAs.

“Lassa fever is an acute viral haemorrhagic fever (VHF) caused by the Lassa virus. The natural reservoir for the virus is the multimammate rat (also known as the African rat). Other rodents can also act as carriers of the virus.

“The disease is also associated with significant loss of livelihood in the communities it ravages. Heads of households are unable to work when exposed to Lassa fever and when other household members are infected, the cost of care and treatment of the disease which is often significant strains existing household income pushing households toward poverty in a swift turn of events.

“Lassa fever outbreaks are highly virulent and the loss of human lives resulting from disease are not just statistics but represent the death of beloved family members, spouses, parents. Healthcare workers are also not excluded as there is a high chance of infection if proper infection prevention and control measures are not observed and experienced healthcare workers may die further straining the country’s already insufficient human resources for health.
While we continue to intensify efforts using an all-of-society approach, the public is hereby advised to note that the virus spreads through:
Direct contact with urine, faeces, saliva, or blood of infected rats.

“Contact with objects, household items, and surfaces contaminated with the urine, faeces, saliva, or blood of infected rats.
Consuming food or water contaminated with the urine, faeces, saliva, or blood of infected rats.
Person-to-person transmission can also occur through direct contact with blood, urine, faeces, vomitus, and other body fluids of an infected person”.

NCDC boss, said the symptoms for Lassa Fever, is like other common illnesses accompanied by a fever, such as malaria. Other symptoms include headache, general body weakness, cough, nausea, vomiting, diarrhoea, muscle pains, chest pain, sore throat, and, in severe cases, bleeding from ears, eyes, nose, mouth, and other body openings. The time between infection and the appearance of symptoms of the disease is 3 to 21 days. Early diagnosis and treatment of the diseases greatly increase the chances of patient survival.

People most at risk for Lassa fever are:
People of all age groups who come in contact with the urine, faeces, saliva, or blood of infected rats.

He therefore advised the populace to ensure they always keep your environment clean, block all holes in your house to prevent the entry of rats and other rodents, cover your dustbins and dispose of refuse properly and communities should set up dump sites far from their homes to reduce the chances of the entry of rodents into their homes.

Also store food items such as rice, garri, beans, corn/maize, etc., in tightly sealed or well-covered containers, avoid drying food stuff outside on the ground or roadside, where it is at risk of contamination and eliminate rats in homes and communities by setting rat traps and other appropriate and safe means.

The Dr. Jide Idris, also spoke on prevention of Cerebrospinal Meningitis (CSM), said Nigeria recorded 4,915 suspected and 380 confirmed cases with 361 deaths across 174 Local Government Areas (LGAs) in 24 States including the Federal Capital Territory.

However, noted that, weather conditions like the dry season that comes with dust, winds, cold nights, and frequent upper respiratory tract infections increase the risk of infection, especially with crowding and poor ventilation.

He said, “The highest burden of CSM in Nigeria occurs in the “Meningitis Belt” which includes all 19 states in the Northern region, the Federal Capital Territory (FCT), and some southern states such as Bayelsa, Cross River, Delta, Ekiti, Ogun, Ondo, Osun).

“In 2023/2024, Nigeria recorded 4915 suspected and 380 confirmed cases with 361 deaths across 174 Local Government Areas (LGAs) in 24 States including the Federal Capital Territory. A total of 2, 281, 750 doses of Men5CV- ACWYX in Bauchi, Gombe, Jigawa and Yobe covering 134 wards in the 13 LGAs. The campaign targeted individuals aged 1-29years, comprising 70% of the population.

He said CSM occurs when there is an acute inflammation of the covering of the brain and the spinal cord. This inflammation can be caused by infection with any of the following organisms – bacteria, viruses, parasites, or fungi. Injuries and certain drugs can also cause such inflammation.

“CSM is an epidemic-prone disease with cases reported all year round in Nigeria. However, weather conditions like the dry season that comes with dust, winds, cold nights, and frequent upper respiratory tract infections increase the risk of infection, especially with crowding and poor ventilation. The highest burden of CSM in Nigeria occurs in the “Meningitis Belt” which includes all 19 states in the Northern region, the Federal Capital Territory (FCT), and some southern states such as Bayelsa, Cross River, Delta, Ekiti, Ogun, Ondo, Osun)”, he stressed.

He lamented that, despite the progress in surveillance, diagnostic capacity, and vaccination over the last few years, CSM remains a priority disease and ever-present public health threat in Nigeria with annual outbreaks in high-burden states that present a challenge for people, health systems, economies, and communities.

He therefore said the disease spreads through,
direct person-to-person contact, including droplets from the nose and throat of infected persons and close and prolonged contact with an infected individual.

According to him, the symptoms for the disease include, fever, headache, nausea and vomiting, photophobia (pain on looking at bright lights), neck stiffness, and altered conscious levels. It may be more difficult to observe these signs in younger children, but irritability, poor feeding, and inactivity are common.

He therefore advised that the citizens should ensure they receive the appropriate vaccination required to protect against meningitis, avoid close and prolonged contact with a confirmed case of CSM including relatives, avoid overcrowding on households, schools dormitories, IDPs, prisons other communal settings and practice proper respiratory hygiene when coughing or sneezing.

Stop indoor air pollution, such as indoor cooking over open flames, practice good personal and hand hygiene by frequently washing hands with soap under running water or using hand sanitisers when necessary, always keep your environment clean and visit the nearest health facility immediately if you notice any of the signs and symptoms associated with CSM.

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Nigeria, 7 others Begin African-led HIV Vaccine Development

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Nigeria and seven other African countries have begun a project to check HIV in the continent.

The project is tagged, Bringing Innovation to cLinical and Laboratory research to end HIV In Africa through New vaccine Technology (BRILLIANT) for HIV vaccine research and development.

Prof Alash’le Abimiku, Executive Director, International Research Centre of Excellence, Institute of Human Virology (IHVN), disclosed this at a press briefing on Thursday in Abuja.

The theme of the briefing was, “HIV Vaccine, Innovation, Science, and Technology Acceleration in Africa (HIV-VISTA) study.

Abimiku said that the countries involved were Nigeria, South Africa, Zambia, Zimbabwe, Tanzania, Uganda, Kenya, and Mozambique.

She said that the objective of the consortium is to evaluate HIV vaccine candidates emanating from the continent.

She added that the initiative was to harness and catalyse African scientists to contribute to an effective HIV vaccine.

“Through these efforts, African institutions will be encouraged to become more autonomous, generate domestic resource support, and form partnerships with the private sector.

“It will possibly create a more sustainable system for HIV vaccine research and development, which is progressively and inordinately dependent on the U.S government,” she said.

She expressed optimism that the partnership will acknowledge the potential of great innovation and science from Africa to solve global health challenges especially those that disproportionally devastate the continent.

Dr Temitope Ilori, Director-General, National Agency for the Control of AIDS (NACA), said that HIV still persisted in spite of efforts at controlling it, hence the need for new tools for prevention.

“The agency has continued to provide preventive measures, but an effective vaccine is crucial to our efforts.

“The BRILLIANT study offers hope for a vaccine tailored to the needs of our population, and Nigeria’s involvement in this global initiative is critical.

“Our participation supports both local and international efforts to end AIDS and brings us closer to a vaccine that could save countless lives across Africa and beyond,” she said.

She said that the BRILLIANT study exemplified the strength of global collaboration and scientific progress.

“Together, we can achieve our shared goal of eradicating HIV worldwide, and Nigeria is honoured to play a vital role in this endeavor,” she said.

Dr Ezekiel James, the Deputy Director of the office of HIV/TB from U.S. Agency for International Development (USAIDS), said that the study offered opportunity for stakeholders to combine efforts to achieve HIV epidemic control.

Similarly, Dr Leo Zekeng, UNAIDS Country Director, stressed the need to engage the community to create awareness of HIV vaccines and similar research that continues to break HIV transmission rates.

The World Health Organisation (WHO) had, on Tuesday, named HIV, malaria, Tuberculosis, and 14 other pathogens as top priorities for new vaccine development.

Also, according to UNAIDS, there are an estimated 39.9 million people living with HIV across the globe in 2023, with an estimated 1.3 million new infections.

Africa has about 25.9 million (65 per cent) of the global burden with Nigeria, contributing about 1.9 million, making it the fourth largest HIV burden country globally.

The USAIDS awarded more than 45 million dollars to the BRILLIANT consortium through a competitive process to implement a cooperative agreement under the BRILLIANT project. (NAN)

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